Disha Vakani was born and brought up in Ahmedabad. Her father Bhim Vakani was one of the most famous Gujarati theatre artists. Disha’s stint with acting started from an early age by acting in some Gujarati plays. She obtained her graduate degree in Dramatic arts from the famous Gujarat College, Ahmedabad.
Disha began her acting career by acting in some stage plays. She became after working in noted plays like Lali Lila and Kamal Patel Vs Dhamal Patel. She made her film debut by acting in a B Grade film titled Kamsin: The Untouched in the year 1997. After which, she played brief or supporting roles in Bollywood films like Devdas, Jodha Akbar and Mangal Pandey: The Rising.
She made her small screen debut by appearing in a guest appearance role in the famous television series called Khichdi in 2004. Her real breakthrough came after she appeared in one of the most famous television series, Taarak Mehta Ka Ooltah Chashmah in the year 2008. She joined the show since its inception in 2008 and is still with the show. Her chemistry with her onscreen husband Dilip Joshi is well appreciated and her role of Dayaben has made her a household name in India. For her splendid performance in the series, she has won numerous Telly awards.