He is the son of former Chief Minister of Tamil Nadu, M. Karunanidhi. He obtained his B.A. degree from Presidency College, Chennai. He has been actively involved in Politics and is presently the South Zone Organising Secretary of the political front DMK (Dravida Munnetra Kazhagam). He has served as the Cabinet Minister of Chemicals and Fertilizers from 2009 to 2013, in Man Mohan Singh’s Cabinet.
He came to limelight after winning from Madurai Constituency during 15th Lok Sabha Elections. He defeated CPM contestant Mohan P. He is an avid follower of Hindu religion while his Father is an atheist.
He is married to Kanthi Azhagiri since 1972. The couple has two children, a son Dayanidhi Azhagiri and a daughter, Kayalvizhi. He and his wife donated cows on his 61st birthday to Madhurai Kallazhagar Temple.