At the age of 12, Margo Harshman relocated toOrange County, California. She attended Hewes Middle School and thereafter she enrolled at Foothill High School. Initially, she used to play softball but quit the game after playing or eight years to try her hands at acting.
Margo started her career as early as two years old. She participated in several beauty pageants. During her childhood, she was busy with gymnastics and dancing and was an ardent piano player. She was signed by a talent manager and made her acting debut at the young age of eight. In her acting career, she is best remembered for her portrayal of a teenaged girl Tawny Dean on the famous Disney Series Evan Stevens. She also reprised her character in the movie titled The Even Stevens Movie in 2003, which was based on the show Even Stevens. Some of her noted television works include The Big Bang Theory and NCIS.