Most prominently, Nani has appeared in the plenty of Telugu movies as well as few of the Tamil movies. However, immediately after his graduation, he decided to work along with Bapu and Srinu Vaitla as an assistant director. Later, he got an opportunity to work as the RJ for the channel named as World Space Satellite located in Hyderabad. He brilliantly performed in the movie titled as Bhale Bhale Magadivoy. However, he received positive responses from the industry and won the Filmfare Critics Award for the category of Best Actor. Additionally, he has also won many popular awards which mainly includes Vijay Award and Toronto After Dark for the category of Best Debut Actor in the year 2011 and as Best Hero in the year 2012 respectively.
Initially, in the year 2008, he got a chance to perform in his Telugu debut movie – Ashta Chamma. His Tamil movies include Veppam, Aaha Kalyanam, and much more. Subsequently, in the year 2013, Nani has also produced the Telugu movie titled as D for Dopidi along with being an excellent narrator. Recently, in the year 2016, he made the cameo appearance in the movie named as Jo Achyutananda in the role of Jyo’s Boyfriend. Additionally, he got a unique opportunity to perform in the dual role as Jairam and Gautham in the suspens thriller movie named as gentleman.