Suchitra Sen made her cinematic debut after her marriage. She made her acting debut with the film Shesh Kothaay in 1952, but it was never released. The following year saw her act opposite Uttam Kumar in Sharey Chuattor, a film by Nirmal Dey. It was a box-office hit and is remembered for launching Uttam-Suchitra as a leading pair. They went on to become the icons for Bengali dramas for more than 20 years, becoming almost a genre unto themselves.
She has acted in 30 of her 60 films with Uttam Kumar. She received a Best Actress Award nomination for the film Devdas, which was her first Hindi movie. Her Bengali melodramas and romances, especially with Uttam Kumar, made her the most famous Bengali actress ever.
The skyrocketing popularity of this romantic pair created a benchmark that remains unchallenged to this day. No other romantic pair in Bengali cinema in the subsequent decades have been able to match up to the magic created by Suchitra Sen and Uttam Kumar.
Suchitra Sen's international success came in 1963, when she won the best actress award at the Moscow International Film Festival for the movie Saat Paake Bandha, becoming the first Indian actress to receive an international film award.
A film critic summed up Suchitra Sen's career and continuing legacy as "one half of one of Indian cinema's most popular and abiding screen pairs, Suchitra Sen redefined stardom in a way that few actors have done, combining understated sensuality, feminine charm and emotive force and a no-nonsense gravitas to carve out a persona that has never been matched, let alone surpassed in Indian cinema"