T. N. Seshagopalan has received considerable acclaim for his rendition of Harikatha and original compositions. His characteristic style includes Nama valis, abhangs, Thillanas and Bhajans. He is equally adept at North Indian ragas making his presence felt in Jugalbandhis on multiple occasions.
He has had the honor of being the cultural ambassador of India to Russia in 1987. He has done musical tours in countries like Australia, Singapore, Malaysia, United States of America, Bahrain and Sri Lanka.
Apart from singing, he has also produced and acted in a Tamil film “Thodi Raagam", in which he played the main lead. In 2006 he was awarded the Sangita Kalanidhi honor by Music Academy.