She came into the limelight soon after she became the first Miss America of Indian Descent. Nina went to the University of Michigan and graduated from there with a degree in Brain Behaviour and cognitive Science. She was interested in beauty contest from her early age so, Niña entered the Miss New York pageant in the year 2013, winning while playing out a "Bollywood Fusion style dance" as her talent.
Soon after she was crowned Miss America, Nina became the target of racist and xenophobic commentary in American social media. She received a lot of negative comments. They normally expressed anti-Arab sentiments and anti-Indian sentiments and also noted the pageant date relative to the September 11 anniversary.
After completing her year as Miss America she started working as a public speaker and advocate for gender equality, diversity, and the promotion of STEM education. She has spoken in both diplomatic and political venues. She also shared the stage with PBS’ NewsHour Weekend anchor Hari Sreenivasan as hosts in September 2014, for a Madison Square Garden talk by Indian Prime Minister Narendra Modi. She even travelled to Vijayawada, Hyderabad, and Mumbai as a part of official March 2016 tour for the U.S. State Department to discuss the importance of Women’s Education.
Davuluri is a spokeswoman for PETA, extending her campaign celebrating diversity to the adoption of mixed-breed dogs from animal shelters. She also met with the then United States President Barack Obama for the Children's Miracle Network Hospital Champions at the White House.